Case Studies

Explore our track record of clinical innovation, strategic outcomes, and transformative healthcare solutions across various medical domains.

Our Case Studies

Explore our track record of clinical innovation, strategic outcomes, and transformative healthcare solutions across various medical domains.

01

Pain Management and Drug Delivery

Clinical Unmet Need

  • Develop an Overt-The-Needle catheter system.

  • Clinical need for a Nerve Block and Tumescent drug delivery system.

  • Unique design for a one hand operation.

  • Products developed with Clinicians and KOLs.

Project Requirements

  • Complete design of the systems with a wide array of designs.

  • Entire system design including catheter, needle, and delivery systems.

  • Fluidics design including flow rate, drug compatibility, delivery.

  • System solution including training, IFU, auxiliary systems.

Execution Strategy

  • Core science for fluidics and simulations of catheter and tip designs.

  • System design with Multiple IP generation.

  • Drug and Device combination system development.

  • Phase gated execution: Feasibility, Design and Development, V&V.

Strategic Outcomes

  • Successful 510(K) and other approvals.

  • Commercial launches in US and OUS.

  • Manufacturing scale up and COGS targets.

  • Clinical success with KOLs and Surgeons.

02

Elastomeric Pumps

Clinical Unmet Need

  • Develop single use infusion pumps for sustained drug delivery.

  • Provide clinical data to support drug delivery regimens.

  • Product lines for short duration (< 2d) and long duration (2d-7d) deliveries of the drugs.

  • Drug compatibility studies.

Project Requirements

  • Fluidics design including the pump, flow restrictors and control systems.

  • Flow rate accuracy.

  • Basal and Bolus drug delivery.

Execution Strategy

  • Core science for fluidics developed with simulation and actual design.

  • System design with Multiple IP generation.

  • Project management with crisp execution.

  • Phase gated execution: Feasibility, Design and Development, V&V.

Strategic Outcomes

  • Successful 510(K) and other approvals.

  • Commercial launches in US and OUS.

  • Manufacturing scale up and COGS targets.

  • Clinical success with KOLs and Surgeons.

03

Manufacturing Yield Improvements and COGS Reduction

Clinical Unmet Need

  • Review existing manufacturing processes and develop Design for Manufacturing (DFM) plans.

  • Reduce overall COGS

Project Requirements

  • Improve COGS of the IOLs to be below $20.00 from $35.00

  • Improve yields from 25% to greater than 90%.

  • Provide V&V for robust outcomes,

Execution Strategy

  • Analysis of the existing processes and materials.

  • Pareto of failures and processes contributing to them.

  • Develop Design of Experiments (DOE), improve and test.

Strategic Outcomes

  • Process optimization with molding and materials with yields >95%.

  • COGS reduction.

  • Material optimization.

  • Significant capacity increase due to improved yields.

04

Single Use Endoscope Systems

Clinical Unmet Need

  • Develop a sustainable technology for single use endoscopy system including Image Processing, Arthroscope and Cloud based Connectivity Solution for improved workflow in the surgical environment.

Project Requirements

  • Develop complete system architecture.

  • Wireless camera system.

  • Design and Develop IPU, Scope and Connectivity solutions.

  • 510(K) submission and approval.

Execution Strategy

  • Project management with crisp execution.

  • CMO selection.

  • Design for Manfuacturability.

  • Phase gated execution: Feasibility, Design and Development, V&V.

Strategic Outcomes

  • Successful 510(K) and other approvals.

  • Commercial launches in US and OUS.

  • Manufacturing scale up and COGS targets.

  • Clinical success with KOLs and Surgeons.

05

Connectivity

Clinical Unmet Need

  • A comprehensive Web based Connectivity platform that enables an integrated cloud based healthcare system.

  • Integrated solution with AI and ML.

  • A total IOT system which is fully integrated.

Project Requirements

  • Develop a comprehensive and integrated solution to manage clinical work flow in a surgical environment with scheduling, sensors, imaging, multimedia integration, post op management.

Execution Strategy

  • Sytem architecture.

  • Azure and cloud storage system selection.

  • Full stack development and Mobile App.

  • Audio, Visual, Images and Video integration.

Strategic Outcomes

  • Successful development of the entire system.

  • Implementation with select sites.

  • AI/ML implementation within the framework.

  • Multiple IP.

Contact Healthcare Evolution, Inc.

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info@healthcareevolution.com

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Confidentiality

We respect the sensitive nature of healthcare innovation and are prepared to sign NDAs before detailed technical discussions.